• Sat. Apr 20th, 2024

Combining Forces: Cartherics and TiCARos Collaborate on Developing Revolutionary CAR-T Cell Treatment for Triple Negative Breast Cancer

BySamantha Jones

Apr 3, 2024
Cartherics and TiCARos collaborate to lead advancement of CLIP-CAR technology

Cartherics, a leading biotechnology company in cancer treatment, has announced a collaboration with TiCARos, a company specializing in developing CAR-T cell products for cancer treatment. Under this partnership, TiCARos will generate CLIP-CAR constructs that will be incorporated into Cartherics’ NK cells to assess their function both in vitro and in vivo.

The collaboration between the two companies aims to develop a CAR-NK product targeting tissue factor (TF) for triple negative breast cancer and other challenging cancers. Each company has nominated a specific tumor antigen to target with the CARs, with Cartherics focusing on TF and TiCARos targeting CD19.

TiCARos’ CLIP-CAR technology modifies the CAR structure to stabilize the immune synapse between immune cells and target tumor cells, resulting in improved efficacy in models. This approach has shown promise in preclinical studies and could potentially revolutionize cancer therapy.

Cartherics’ CEO, Professor Alan Trounson, believes that combining TiCARos’ CLIP-CAR technology with Cartherics’ allogeneic NK cell platform has the potential to enhance the effectiveness of cancer therapies. By collaborating with innovative companies like TiCARos, Cartherics aims to build a leading portfolio of therapeutic products for cancer treatment.

If the research collaboration yields positive results, Cartherics and TiCARos will negotiate a development and commercialization agreement for their CAR-NK therapeutic approach. This partnership is expected to accelerate pipeline programs and expand the use of TiCARos’ technology beyond autologous cell therapies.

By Samantha Jones

As a dedicated content writer at newszxcv.com, I bring a passion for storytelling and a keen eye for detail to every piece I create. With a background in journalism and a love for crafting engaging narratives, I strive to deliver informative and captivating content that resonates with our readers. Whether I'm covering breaking news or delving into in-depth features, my goal is to inform, entertain, and inspire through the power of words. Join me on this journey as we explore the ever-evolving world of news together.

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