Space Biology on ISS

NASA

SPACELINE Existing Awareness Lists are distributed by way of listserv and are out there on the NASA Activity Book web page at https://taskbook.nasaprs.com/Publication/spaceline.cfm. 

Please send any correspondence to Shawna Byrd, SPACELINE Existing Awareness Senior Editor, [email protected].

Contact for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an post that has not too long ago published or will publish in the upcoming weeks inside a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your post to the e mail address talked about above. Articles received by Wednesday will seem inside that week’s list—articles received right after Wednesday will seem the following week.

Papers deriving from NASA assistance:

1

Faerman A, Clark JB, Sutton JP.

Neuropsychological considerations for lengthy-duration deep spaceflight.

Front Physiol. 2023 Could 1914:1146096. Critique.

https://doi.org/ten.3389/fphys.2023.1146096

Note: This post is portion of Investigation Subject “Brains in Space: Effects of Spaceflight on the Human Brain and Behavior-Volume II” (https://www.frontiersin.org/investigation-subjects/47491/brains-in-space-effects-of-spaceflight-on-the-human-brain-and-behavior—volume-ii#overview). The Investigation Subject also contains articles from prior Existing Awareness Lists #1,041 https://doi.org/ten.3389/fphys.2023.1141078 and #1,046 https://doi.org/ten.3389/fncir.2023.1135434. This post may well be obtained on the net with no charge.

Journal Effect Issue: 3.342

Funding: “Support from the Translational Investigation Institute for Space Overall health by way of NASA Cooperative Agreement NNX16AO69A is gratefully acknowledged. JS is supported by the Friedkin Chair for Investigation in Sensory Technique Integration and Space Medicine at Baylor College of Medicine.”

two

Shelhamer M, Antonsen E, Reynolds R.

The need to have for a systems method in spaceflight wellness and medicine.

2023 IEEE Aerospace Conference. 2023 Could 15.

https://doi.org/ten.1109/aero55745.2023.10115773

PI: M. Shelhamer

Note: This post is a conference proceeding published by a peer-reviewed journal.

Journal Effect Issue: 0.88

Funding: “MS is supported by NASA 80NSSC19K0487.”

three

Shelhamer M, Gersh JR.

A mission architecture to integrate human and spacecraft functional efficiency.

2023 IEEE Aerospace Conference. 2023 Could 15:1-eight.

https://doi.org/ten.1109/aero55745.2023.10115715

PI: M. Shelhamer

Note: This post is a conference proceeding published by a peer-reviewed journal.

Journal Effect Issue: 0.88

Funding: “MS is supported by NASA 80NSSC19K0487.”

four

Hilditch CJ, Pradhan S, Costedoat G, Bathurst NG, Glaros Z, Gregory KB, Shattuck NL, Flynn-Evans EE.

Sex variations in perceptions of sleep inertia following nighttime awakenings.

Sleep Adv. 20234(1):zpac043.

https://pubmed.ncbi.nlm.nih.gov/37193286

Note: This post may well be obtained on the net with no charge.

Journal Effect Issue: Not out there for this journal

Funding: “This function was supported in portion by the Naval Healthcare Investigation Center’s Naval Sophisticated Healthcare Improvement Plan (MIPR N3239820WXHN007) and the National Aeronautics and Space Administration Airspace Operations and Security Plan, Technique Wide Security.”

five

Saint-Guillain M, Vanderdonckt J, Burny N, Pletser V, Vaquero T, Chien S, Karl A, Marquez J, Wain C, Comein A, Casla IS, Jacobs J, Meert J, Chamart C, Drouet S, Manon J.

Enabling astronaut self-scheduling applying a robust sophisticated modeling and scheduling program: An assessment for the duration of a Mars analogue mission.

Adv Space Res. 2023 Apr five. On the web ahead of print.

https://doi.org/ten.1016/j.asr.2023.03.045

Note: From the abstract: “Human lengthy duration exploration missions (LDEMs) raise a quantity of technological challenges. This paper addresses the query of the crew autonomy: as the distances boost, the communication delays and constraints have a tendency to stop the astronauts from becoming monitored and supported by a true time ground manage.”

Journal Effect Issue: 2.611

Funding: T. Vaquero and S. Chien are affiliated with NASA Jet Propulsion Laboratory. J. Marquez is affiliated with NASA Ames Investigation Center.

six

Schroeck H, Whitty MA, Martinez-Camblor P, Voicu S, Burian BK, Taenzer AH.

Anaesthesia clinicians’ perception of security, workload, anxiousness, and pressure in a remote hybrid suite compared with the operating area.

Br J Anaesth. 2023 Could 16S0007-0912(23)00203-9. On the web ahead of print.

https://pubmed.ncbi.nlm.nih.gov/37202262

Journal Effect Issue: 11.719

Funding: B.K. Burian is affiliated with NASA Ames Investigation Center.

7

Li M, Lee JD.

Modeling purpose alignment in human-AI teaming: A dynamic game theory method.

Proc Hum Variables Ergon Soc Annu Meet. 2022 Oct66(1):1538-42.

https://doi.org/ten.1177/1071181322661047

PI: J.D. Lee

Note: This post is a meeting proceedings that published in peer-reviewed Sage journals. This post may well be obtained on the net with no charge.

Journal Effect Issue: 3.598

Funding: “This function was supported by NASA Human Investigation Plan No. 80NSSC19K0654.”

eight

Buettmann EG, Chlebek C, Lockard CA, Clayton SW, Lewis KJ, Collins KH.

Post or perish? Social media approaches for disseminating orthopedic investigation.

J Orthop Res. 2023 Could ten. On the web ahead of print.

https://doi.org/ten.1002/jor.25588

PI: E.G. Buettmann

Note: This post may well be obtained on the net with no charge.

Journal Effect Issue: 3.103

Funding: “Dr. Evan Buettmann was supported by the Translational Investigation Institute for Space Overall health (TRISH) by way of Cooperative Agreement with NASA (NNX16AO69A). Dr. Kelsey Collins was supported by NIAMS (Grant K99AR078949).”

_______________________________________________________

Other papers of interest:

1

Almosa AS, Lockwood MB, Green SJ.

Effects of spaceflight on the human gastrointestinal tract microbiome.

J Indian Inst Sci. 2023 Could 23. Critique.

https://doi.org/ten.1007/s41745-023-00384-7

Note: From the abstract: “In this brief assessment, we summarize the present state of know-how on the impact of space travel on the human gut microbiome, which includes investigation styles that involve animals (rodents), humans, and novel simulations. Experiments have been carried out below circumstances of spaceflight, ground-primarily based, and analogous flight simulation.”

two

Ejova A, Searston RA, Stephens R, Semmler C.

Clear pondering in deep space: A guide by cognitive scientists.

In: de Zwart M, Henderson S, Culton J, Turnbull D, Srivastava A, eds. Human Utilizes of Outer Space: Return to the Moon. Singapore: Springer Nature Singapore, 2023. p. 31-47.

https://doi.org/ten.1007/978-981-19-9462-three_three

three

Oxlad M, Whitburn S, Carter AJ.

Optimizing mission achievement: A holistic method to choosing the finest men and women to travel to space.

In: de Zwart M, Henderson S, Culton J, Turnbull D, Srivastava A, eds. Human Utilizes of Outer Space: Return to the Moon. Singapore: Springer Nature Singapore, 2023. p. five-29.

https://doi.org/ten.1007/978-981-19-9462-three_two

four

Sakaki T, Koizumi T, Ikeido Y, Soga K, Wakabayashi K, Hoson T.

Boost in steryl glycoside levels and stimulation of lipid raft formation in azuki bean epicotyls below hypergravity circumstances.

Life Sci Space Res. 2023 Aug 2338:53-eight.

https://doi.org/ten.1016/j.lssr.2023.05.005

Note: A centrifuge was applied in this study.

five

Lv W, Peng X, Tu Y, Shi Y, Song G, Luo Q.

YAP [Yes-associated protein] inhibition alleviates simulated microgravity-induced mesenchymal stem cell senescence by way of targeting mitochondrial dysfunction.

Antioxidants. 2023 Apr 2312(five):990.

https://doi.org/ten.3390/antiox12050990

Note: A 2D clinostat was applied in this study. From the abstract: “Weightlessness in space leads to bone loss, muscle atrophy, and impaired immune defense in astronauts. Mesenchymal stem cells (MSCs) play essential roles in preserving the homeostasis and function of the tissue. Nevertheless, how microgravity impacts the qualities MSCs and the connected roles in the pathophysiological adjustments in astronauts stay barely recognized.” This post is portion of Subject “Advances in Astrobiology” (https://www.mdpi.com/subjects/T9B7L6S956). This post may well be obtained on the net with no charge.

six

Shamei A, Sóskuthy M, Stavness I, Gick B.

Postural adaptation to microgravity underlies fine motor impairment in astronauts’ speech.

Sci Rep. 2023 Could 2213:8231.

https://pubmed.ncbi.nlm.nih.gov/37217497

Note: From the post: “The authors declare that the information applied inside this evaluation was obtained from publicly out there sources, and all investigation was completed in accordance with human investigation ethics recommendations and regulations. The National Aeronautics and Space Administration (NASA) delivers audio and video for a choice of missions by way of the public NASA photos archive, which consists of audio and video files of Astronaut interviews for chosen missions. Audio files from each and every mission have been chosen for the reason that they function substantial speech information (in between 70 and 120 s of speech) of astronauts instantly prior to and right after their respective missions, permitting direct comparisons of vowel space prior to and right after adaptations to microgravity. We evaluated vowel formants from 4 astronauts across 4 STS missions: (i) STS-129 (ii) STS-133, (iii) STS-134, and (iv) STS-135.” This post may well be obtained on the net with no charge.

7

Yue Y, Yang J-Q, Lu S-Y, Ge J, Nie H-Y, Liu K-G, Liu F, Li H, Yan H-F, Zhang T, Sun P-M, Sun H-W, Yang J-W, Zhou J-L, Cui Y.

Simulated microgravity altered the proliferation, apoptosis, and extracellular matrix formation of L929 fibroblasts and the transforming development issue-β1/Smad3 signaling pathway.

Skin Res Technol. 2023 Could 829(five):e13341. On the web ahead of print.

https://doi.org/ten.1111/srt.13341

Note: A rotary cell culture program was applied in this study. This post may well be obtained on the net with no charge.

eight

Zhang Y, Huang H, Yao C, Sun X, He Q, Choudharyc MI, Chen S, Liu X, Jiang N.

Fresh Gastrodia elata blume alleviates simulated weightlessness-induced cognitive impairment by regulating inflammatory and apoptosis-connected pathways.

Front Pharmacol. 2023 Could 314:1173920.

https://pubmed.ncbi.nlm.nih.gov/37205911

Note: Hindlimb unloading study. This post is portion of Investigation Subject “Exploring the Essential Targets and Compounds That Manipulate Brain Neurocircuits Against Mental Issues and Psychiatric” (https://www.frontiersin.org/investigation-subjects/44928/exploring-the-important-targets-and-compounds-that-manipulate-brain-neurocircuits-against-mental-issues-and-psychiatric#overview). The Investigation Subject also contains an post from prior Existing Awareness List #1,050 https://doi.org/ten.3389/fphar.2023.1167398. More articles will be forthcoming and may well be discovered in the hyperlink to the Investigation Subject. This post may well be obtained on the net with no charge.

9

Sim HJ, So HS, Poudel SB, Bhattarai G, Cho ES, Lee JC, Kook SH.

Osteoblastic Wls ablation protects mice from total physique irradiation-induced impairments in hematopoiesis and bone marrow microenvironment.

Aging Dis. 2023 Jun 114(three):919-36.

https://pubmed.ncbi.nlm.nih.gov/37191410

Note: This post may well be obtained on the net with no charge.

ten

Zhang Q, Gerweck LE, Cascio E, Gu L, Yang Q, Dong X, Huang P, Bertolet A, Nesteruk KP, Sung W, McNamara AL, Schuemann J.

Absence of tissue-sparing effects in partial proton FLASH irradiation in murine intestine.

Cancers (Basel). 2023 Apr 1315(eight):2269.

https://pubmed.ncbi.nlm.nih.gov/37190197

Note: This post may well be obtained on the net with no charge.

11

Waldbaum JDH, Xhumari J, Akinsuyi OS, Arjmandi B, Anton S, Roesch LFW.

Association in between dysbiosis in the gut microbiota of principal osteoporosis individuals and bone loss.

Aging Dis. 2023 Apr 28. Critique.

https://pubmed.ncbi.nlm.nih.gov/37199579

Note: This post may well be obtained on the net with no charge.

12

Badakva AM, Miller NV, Zobova LN.

Integration of vestibular, visual, and proprioceptive inputs in the cerebral cortex for the duration of movement manage.

Hum Physiol. 2023 Apr 2749(two):176-82. Critique.

https://doi.org/ten.1134/S0362119722600515

13

Kelly KR, Palombo LJ, Jensen AE, Bernards JR.

Efficacy of closed cell wet-suit at several depths and gas mixtures for thermoprotection for the duration of military education dives.

Front Physiol. 2023 Could 2414:1165196.

https://doi.org/ten.3389/fphys.2023.1165196

Note: This post may well be obtained on the net with no charge.