Balto and his owner, Gunnar Kasson in 1925. Credit: Photo courtesy of Cleveland Public Library/Photograph Collection

Do you remember the story of Balto? In 1925, the town of Nome, Alaska, was facing a diphtheria outbreak. Balto was a sled dog and a very good boy who helped deliver life-saving medicine to the people in the town. Balto’s twisty tale has been told many times, including in a 1990s animated movie in which Kevin Bacon voiced the iconic dog.

But last month, scientists uncovered a new side of Balto. They sequenced his genes and discovered the sled dog wasn’t exactly who they expected. The study published in the journal Science, was part of a project called Zoonomia, which aims to better understand the evolution of mammals, including our own genome, by looking at the genes of other animals—from narwhals to aardvarks. 

Guest host Flora Lichtman talks with Dr. Elinor Karlsson, associate professor in Bioinformatics and Integrative Biology at the UMass Chan Medical School and director of Vertebrate Genomics at the Broad Institute of MIT and Harvard; Dr. Katie Moon, post-doctoral researcher who led Balto’s study; and Dr. Beth Shapiro, professor of ecology and evolutionary biology at UC Santa Cruz, who coauthored the new study on Balto and another paper which identified animals that are most likely to face extinction. 

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